多索茶碱联合布地奈德治疗支气管哮喘的临床疗效探析
支气管哮喘简称哮喘,主要由较多炎性细胞反应性产生,常伴有变化不定的呼吸气流受阻现象[1]。其临
床症状多表现在喘息、咳嗽、气急和胸闷等现象,严重者甚至出现呼吸衰竭等症。多索茶碱是一种新型药物,可直接作用在支气管平滑肌处且不良反应少,从而抑制哮喘[2]。该院对2013年1月—2015年12月所收治的78例患者在支气管哮喘疾病治疗过程中使用多索茶碱联合布地奈德药物进行治疗,取得满意效果,现报道如下。1资料与方法
1.1一般资料
方便选取在该院收治的支气管哮喘住院患者78例,纳入标准:①患者均符合中华医学会呼吸病学会制定的哮喘诊断标准和分度标准;②患者在哮喘发作前12h内未服用治疗平喘药物。排除标准:患者存在严重
DOI:10.16662/https://www.360docs.net/doc/fc3680069.html,ki.1674-0742.2018.18.095
多索茶碱联合布地奈德治疗支气管哮喘的临床疗效探析
肖麟蔚
福建省龙岩市中医院肺病科,福建龙岩364000
[摘要]目的探讨分析多索茶碱联合布地奈德治疗支气管哮喘的临床疗效。方法方便选取2013年1月—2015年12月在该院收治的支气管哮喘住院患者78例,随机分成两组,对对照组、研究组患者分别应用常规氨茶碱和多索茶碱联合布地奈德进行治疗,两组疗程均为2周,对比两组患者治疗效果。结果患者治疗结果方面,研究组治疗效果有效率为82.1%,对照组治疗效果为56.4%,研究组治疗效果明显优于对照组(χ2=6.363,P<0.05)。治疗前两组患者的肺
功能差异无统计学意义(t=1.254,2.214,1.264,1.057,P>0.05)。结论对支气管哮喘患者进行多索茶碱联合布地奈德治疗效果比茶碱或氨茶碱比较起效快,有效改善患者的呼吸功能,减少患者的临床症状,依从性高且不良反应少,安全性高,具有临床应用价值,值得进一步推广。
[关键词]多索茶碱;布地奈德;支气管哮喘;疗效;肺功能
[中图分类号]R4[文献标识码]A[文章编号]1674-0742(2018)06(c)-0095-03 Therapeutic Effect of Doxofylline Combined with Budesonide on Bronchial Asthma
XIAO Lin-wei
Department of Pulmonary Disease,Traditional Chinese Hospital,Longyan,Fujian Province,364000China
[Abstract]Objective This paper tries to explore the clinical efficacy of doxorine combined with budesonide in the treat?ment of bronchial asthma.Methods78patients with bronchial asthma admitted to the hospital from January2013to De?cember2015were convenient selected and randomly divided into two groups.Patients in the control group and study group were treated with conventional aminophylline and doxofylline combined with budesonide treatment,two courses of treatment were two weeks,the treatment effect of the two groups of patients were compared.Results In terms of patient outcomes,the effective rate of the treatment group was82.1%in the study group and56.4%in the control group.The treatment effect of the study group was significantly better than that of the control group(χ2=6.363,P<0.05).There was no significant differ?ence in lung function between the two groups before treatment(t=1.254,2.214,1.264,1.057,P>0.05).Conclusion The ef?fect of doxofylline combined with budesonide on bronchial asthma patients is faster than that of theophylline or amino?phylline,which can effectively improve the patient's respiratory function,reduce the patient's clinical symptoms,high com?pliance and less adverse reactions,high safety,with clinical application value,worth further promotion.
[Key words]Docetoline;Budesonide;Bronchial asthma;Efficacy;Lung function
[作者简介]肖麟蔚(1969-),男,福建龙岩人,本科,副主任医
师,研究方向:呼吸内科的常见疾病及急危重症的抢救。
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China&Foreign Medical Treatment中外医疗