美国救星瓶使用手册Instruction Manual

美国救星瓶使用手册Instruction Manual
美国救星瓶使用手册Instruction Manual

INSTRUCTION MANUAL

4000UF & 6000UF ?

e

l

t

t

o

b

Dear user

I developed the LIFESAVER after I saw the tragic waste

of life and serious problems caused by the lack of safe drinking water in the wake of the tsunami in December 2004 and then again the following year on August 29, 2005 when Hurricane Katrina hit Louisiana. I could not believe it. I really felt that something had to be done. It took a little while and some very frustrating prototypes but eventually I did it.

LIFESAVER bottle uses a highly advanced ultra filtration system, originally developed for industrial applications. LIFESAVER bottle will remove bacteria, viruses, cysts, parasites, fungi and all other microbiological waterborne pathogens. It does all this without the aid of any foul tasting chemicals like iodine or chlorine. As I pointed out to a friend one day “using chemicals to kill bacteria is not always effective and anyway all you are doing is drinking a chemical cocktail with some dead pathogens in it.” Whilst inventing LIFESAVER bottle I also invented FAILSAFE technology. In simple terms this means that when the cartridge has expired it shuts off, preventing the user from drinking contaminated water. Just change the cartridge and continue to use.

LIFESAVER bottle has been designed to help save lives supplying people with clean pathogen-free drinking water. Treated with care and respect you can expect many years of trouble-free use. Should you have any questions or concerns please feel free to contact me directly at michael@https://www.360docs.net/doc/1212786090.html,

Michael W. Pritchard M.W.M.Soc

LIFESAVER systems

Inventor – CEO

UK

Contents

4 Using your lifesaver bottle

4 Priming the cartridge

5 Drinking from the bottle

6 Before undertaking any trip

7 Instructions for routine use

7 Choosing your water source

8 M aintenance and Care of your

lifesaver bottle

8 Front-side washing at home & in the field

10 Installing / changing the UF cartridge

12 Using the pre-filter

1 Replacing the activated carbon filter

14 Replacing the teat

14 Maintaining the pump

15 Failsafe T echnology

15 Membrane integrity check

16 Long term storage

17 frequently asked Questions

18 T echnical information

19 Warranty

U S I N g y O U R B O T T L E

chew-proof drinking teat

cap seal

cap

twist lock pump handle

anti-slip base

ultra filtration membranes pump tube replaceable activated carbon filter

replaceable UF cartridge LIFESAVER bottle 750 ml

capacity protective sleeve

membrane protection grills

removable base containing

replaceable pre-filter disc / scavenging

sponge removable strap

4

water-tight snap-fit lid

Drinking from the lifesaver bottle Having primed the cartridge, refill your LIFESAVER bottle and familiarise yourself with it. Practice drinking from the teat. This may sound a strange thing to say but because the water is under pressure it will flow from the teat without you having to suck. If you over pump the bottle and are not used to the flow you may get rather wet. Whilst drinking keep your lips closed around the teat.Pushing the teat ? closed with your teeth will halt the flow. you can continue to close it fully with your teeth or just push it fully closed with clean hands.any position operation

LIFESAVER bottle has been designed to work at any angle and on any axis. This means that in effect it will work in any position. Not only are you able to drink straight from the teat but you can also fill mugs, water bottles, pans and other water storage vessels.

*Do not over pump your LIFESAVER bottle. It is effectively a pressurised vessel and should be handled with caution. you will discover in a very short time that only a few pumps are needed to induce water flow. If you continue to over pump the bottle, teat will open. This is a safety feature.

** In order to maintain the quality of the

membranes after manufacture a small amount of glycerine is used to coat their surface. Priming

first time use

Priming the cartridge

In order to use LIFESAVER bottle you must first prime the UF cartridge.

T o prime the UF cartridge:

? Ensure the cap is firmly tightened.? Ensure that the snap-fit lid is on.? U nscrew the base, fill with water and screw to close.

? T wist handle and pump a few times.*? T wist pump handle to lock.? A llow to stand for 5 minutes.

? U nscrew the base and discarded the water and refill again. ? O pen the teat, pump the LIFESAVER bottle. Water will begin to flow. This water should be discarded and should not be drunk.**

? R efill and repeat the previous step 2 more times.

? y our LIFESAVER bottle is now ready to use.you may notice the water takes a while to come through. This is normal and part of the priming process. After a 2- refills the water will flow freely.

iMPOrTaNT!

you may notice on priming the cartridge that the water water contains grey/black particles. This is simply harmless

carbon dust from the activated carbon filter and once the cartridge has been flushed through a couple of times, this will disappear.

U S I N g y O U R B O T T L

E

UK 5

U S I N g y O U R B O T T L E

Before you undertake any trip…It is important that you follow these few simple steps.

? E nsure that the cartridge is correctly

and firmly in place. (‘How to install or replace a LIFESAVER bottle UF cartridge’ - page 10)

? F lush the bottle through a couple of times with clean water in order to check the flow rates.

? C heck the pump is working

smoothly and add a small amount of silicone grease (provided) to the piston head as required. (‘Maintenance and care’ - page 14) Failure to do this will result in the premature wearing of the o-ring.? E nsure that you have installed a new activated carbon filter.? P erform a membrane integrity check. (page 15)

iMPOrTaNT!

Always keep bottle cap firmly screwed on when in the field. Do not remove bottle cap unless changing the carbon filter or the LIFESAVER cartridge and then only after following instructions (see instructions below).

The bottle cap should remain tightly closed at all times. This holds the LIFESAVER cartridge firmly in place and ensures that contaminated water does not enter the clean water side of

the bottle.

6

instructions for routine use

Once you are familiar with your LIFESAVER bottle, the instructions are simple. FILL ? PUMP ? DRINK??E nsure that the drinking teat is closed and that the snap-fit lid is on securely.

?U nscrew the bottle base.

?F ill your LIFESAVER bottle with the desired amount of water.

?S crew the base back on.

?T wist to unlock the pump handle and pump a few times.*

?T wist the pump handle to lock closed.

?O pen the snap-fit lid, pull teat with teeth or clean hands and drink.?C lose teat and ensure snap fit lid is firmly closed by applying pressure. Choosing your water source Always choose the cleanest water source available. LIFESAVER bottle will work with high turbidity water though the dirtier the water, the quicker the cartridge will expire. Using the

pre-filter disc will prolong the life of your LIFESAVER bottle.

iMPOrTaNT!

Do not allow grit, sand or other abrasive matter to enter the bottle. If this happens it should be removed. Abrasive matter remaining in the bottle will cause the base seals to prematurely wear. This may cause your LIFESAVER bottle to leak and may void your warranty.

If the seal at the base begins to wear, applying a thin layer of silicone grease (supplied) to the inside base of the bottle will help seal the bottle and prevent leakage.

For situations where grit and other abrasive matter is difficult to avoid a separate o-ring seal may be purchased. LIFESAVER bottles purchased after December 2007 include this O-ring

as standard.

*Do not over pump your LIFESAVER bottle. It is effectively a pressurised vessel and should be handled with caution. you will discover in a very short time that only a few pumps are needed to induce water flow. If you continue to over pump the bottle, the

teat will open. This is a safety feature.

UK

U

S

I

N

g

y

O

U

R

B

O

T

T

L

E

7

M A I N T E N A N C E A N D C A R E

Maintenance and Care

The unique ultra filtration membranes used in the LIFESAVER bottle have been developed to deliver a high volume throughput at very low pressures. The capacity of your LIFESAVER cartridge will depend on the water quality.

LIFESAVER bottle is designed to filter water only. It is not designed for filtering sugared or carbonated drinks, alcohol or any other liquids.

LIFESAVER bottle will not filter out salts.If you suspect the cartridge has been damaged in some way always replace the cartridge immediately and wash the bottle thoroughly in a mild disinfectant. In any event perform a Membrane Integrity Check (page 15)

LIFESAVER bottle has a long shelf life. It can be stored unused for up to years. Once the bottle has been used, the cartridge will last up to a further 2 years dependent upon usage conditions. Please check the end of shelf life date on your product.

front-side washing lifesaver bottle Over the life of the membranes

particulate matter will build up on its surface. The filter cartridge’s unique

design induces particulate matter to form a caking layer on its external surfaces. T o reduce this build-up you should perform a front-side wash on a regular basis.

8

iMPOrTaNT!

DO NOT subject the LIFESAVER bottle/ cartridge to shock or other misuse such as inserting objects into the cartridge.DO NOT fill the cartridge up with any liquids other than water as this may cause irreparable damage and in any event will void your warranty.

DO NOT allow large, sharp or abrasive matter such as stones, glass, metal and other detritus to enter the cartridge. The pre-filter should always be used.DO NOT use detergents or other cleaning agents to clean your

LIFESAVER bottle / cartridge except where specified.

T o perform a front-side wash: in the field

as possible.

at home

1. E

2.

. P

4. K

5. S

snap-fit lid. 3 (THIS IS VERy IMPORTANT as it

replaced.)

6. I

7. F

necessary.

8.

9. T

10. g

UK

closed but be careful

M A I N T E N A N C E A N D C A R E

iMPOrTaNT!

Changing your LIFESAVER cartridge in the field causes a heightened risk of cross contamination during cartridge change over. Should you need to

replace your cartridge, ensure you have clean, dry hands. Once the expired cartridge is removed, clean, disinfect and dry the bottle before inserting the new cartridge. This will reduce the risk of cross contamination.

How to install or change a lifesaver bottle Uf cartridge Before changing your cartridge, try front-side washing first to remove particulate matter (page 8). This may just extend the life of your cartridge long enough to meet your requirements.

As the LIFESAVER cartridge has been designed for exceptional service life, it is rare that you will need to change the cartridge whilst in the field. However, should it be necessary, it is very

important that you follow the instructions carefully:

? E mpty the bottle of water. Empty the

teat end of water.

?

P

10

M A I N T E N A N C E A N D C A R E

UK

11

M A I N T E N A N C E A N D C A R E

Using your pre-filter disc

your LIFESAVER bottle comes with a pre-filter disc already fitted inside. your Pre-filter disc is designed to extend the life of your LIFESAVER bottle.

your pre-filter disc may also be used as a sponge. Use it to soak up water from those hard to reach places like cracks in rocks or shallow puddles. Simply squeeze the contents of the sponge into the bottle.

When the pre-filter disc has collected muck, dirt, sand and other debris these should be washed free from

the pre-filter disc before re-inserting.If the hole is taking a while to close-up simply remove the pre-filter disc, place in water and squeeze it a couple of times.you may find that when using the pre-filter disc that water can take some time to enter the bottle. If the pre-filter disc is dry you can improve the flow rate by immersing it in the water source and squeezing it a few times.

Over time the pre-filter disc will become worn. It should be replaced if it becomes torn. In any event it should be replaced every 6-12 months dependent on use.

iMPOrTaNT!

The pre-filter must always remain in the bottle.

12

replacing your activated carbon filter The activated carbon filter is made of high specification activated carbon which reduces a broad spectrum of chemical residues including pesticides, endocrine disrupting compounds, medical residues and heavy metals.

It is designed to last for approximately

250 litres.

1. Empty LIFESAVER bottle of water.

2. I nstall pre-filter disc in base of bottle and firmly screw up base.

. Pump the handle 0 times.*

4. Unscrew the cap.

5. U nscrew the old activated carbon filter and replace with a new one.

6. Firmly screw up the cap.

7. you may now slowly unscrew the base.

8. I f this proves difficult leave the teat in the open position for a few minutes and try again.

After any trip and or when storing LIFESAVER bottle the activated carbon filter should be removed and discarded. Only replace with a new one immediately before your next trip.

M

A

I

N

T

E

N

A

N

C

E

A

N

D

C

A

R

E

UK

iMPOrTaNT!

Do not replace your carbon

filter in the field unless

absolutely necessary. When

replacing the carbon filter you

must follow these instructions.

Failure to do so may cause contaminated water to pass

through to the drinking water

side.

Leaving the activated carbon

filter inside the bottle whilst in

long term storage may cause microbiological growth to

occur. This will not have come

from the bottle but may come

from the user’s saliva. Always

remove and discard the

activated carbon filter when

storing LIFESAVER bottle

long term.

1

*iMPOrTaNT!

If you do not pump the handle 0 times the cartridge will disengage from the seal and you risk contaminating the clean water side of the bottle.Do not over tighten the activated carbon filter as

this risks damage

replacing the teat

LIFESAVER bottle’s teat has been designed to be non-tasting, replaceable and

chew-proof. Unlike many other systems LIFESAVER bottle has been designed so that its teat can be easily changed. Over time the teat will wear. When it

becomes necessary to replace follow these instructions.

1. Open the snap-fit lid.

2. Pull out the teat. . R emove your new teat from its packaging.

M A I N T E N A N C E A N D C A R E

14

UK failsafe?technology

There are several aspects of this technology

that increase the safety and reliability of your

LIFESAVER bottle.

auto shut Off

As the LIFESAVER cartridge nears the end of

its service life a greater and greater number

of pumps are required to induce water to flow. There will come a point at which despite continuous pumping water does not flow. This is the auto shut off feature of FAILSAFE working. your cartridge has now expired and you must now change it. Before changing however, perform a front side wash as the membranes may just be covered with particulate matter. Membrane integrity

The ultra filtration membranes used in your LIFESAVER bottle have been precision engineered. They have been integrated into a robust cartridge format and have been designed for long service life. If treated incorrectly they are liable to break. There are several reasons why

a membrane might break. DO NOT subject the bottle/cartridge to shock or other misuse such as inserting objects into the cartridge or filling the cartridge up with anything other than water. DO NOT allow large, sharp or abrasive matter such as stones, glass, metal etc. to enter the cartridge. Membrane integrity check

your LIFESAVER bottle has been designed to work at any angle and on any axis. If water does not flow at all angles and axes then you have damaged the membranes in some way and you must replace the cartridge immediately.

M

A

I

N

T

E

N

A

N

C

E

A

N

D

C

A

R

E

iMPOrTaNT!

This integrity check should

be performed on a regular

basis and every time the

bottle has been subjected

to shock or you suspect

damage may have

occurred for any reason

to the bottle or cartridge membranes.

15

long term storage

If storing LIFESAVER bottle for a prolonged period of time

(i.e. between trips) you should always perform a front-side wash. Ensure that no water remains in the teat end of the cartridge. you will need to discard the activated carbon filter and the pre-filter disc.

sterilisation

Fill a jug or similar vessel with 1 litre of tap water and add ml of Milton Fluid (or compatible sterilising fluid) to make a sterilising solution. Fill the LIFESAVER bottle with the sterilising solution to the top of the cartridge fins. gently agitate. Leave for 1 hour. Invert and leave for a further 1 hour. Now pump the sterilising solution through the bottle and discard to drain.

Refill LIFESAVER bottle with fresh tap water and pump through to drain. Dis-assemble the bottle and remove the cartridge. Remove the cap and teat from the cap. Clean thoroughly and dry. Reassemble the bottle, screw the cap onto the cartridge and replace the snap-fit lid.

Clean the bottle and base by hand with a mild washing up liquid ensuring that all dirt and other particulate matter is removed. Rinse and dry thoroughly.

Re-assemble LIFESAVER bottle. Ensure that the bottle is fully

assembled with the snap-fit lid on. you may notice a small amount of condensation appear on the inside of the bottle over time. This is natural and is required to keep the membranes in good order.When you plan to use LIFESAVER bottle again just flush the bottle through twice and it is ready to use.

If you notice any bacteriological growth on the inside of the bottle then clean both bottle and cartridge as advised, (page 8) and perform sterilisation again.

Before first use LIFESAVER bottle should be kept in a dry place. After first use the product should be protected against freezing.

M A I N T E N A N C E A N D C A R E

16

UK frequently asked questions

Q. i am finding it difficult to

unscrew the base

A. I f you find it difficult to remove the base, this could be due to an over pressurisation. T o solve this, leave the teat in the open position for a while and try again. Alternatively you may have over tightened

the base. This will require either access to hot water which will help loosen the base or good old fashioned elbow grease.

you may also try pumping the bottle 8-10 times and try again. Sometimes this will loosen the base.

Q. W here do i purchase

additional cartridges?

A. R eplacement cartridges and other LIFESAVER bottle consumables are available from the dealer where you purchased your LIFESAVER bottle. Alternatively go to our website https://www.360docs.net/doc/1212786090.html, and buy online.

Q. W here do i dispose of spent cartridges?

A. T he cartridge is made of recyclable plastic and should

be disposed of at a recycling centre. If this is not possible, you can dispose of it in your normal household waste.Q i am pumping but no water is coming out

A. y our cartridge may have expired

or may require a front-side wash (page 8).

Q T he pumping action has

become stiff

A. T he most likely reason for this

is a lack of silicone in the pump (maintaining the pump -

page 14).

Q W here can i get replacement parts?

A. L IFESAVER bottle has been engineered so that all parts are replaceable. Please go to the

dealer where you purchased

your LIFESAVER bottle.

Alternatively go to our website

https://www.360docs.net/doc/1212786090.html, and

buy online.

For a list of these and other

frequently asked questions

please visit our website

https://www.360docs.net/doc/1212786090.html,.

F

R

E

q

U

E

N

T

L

y

A

S

K

E

D

q

U

E

S

T

I

O

N

S

17

Performance and technical data Minimum operating temperature >0 o C ( 2 o F)Maximum operating temperature 50 o C (122 o F)Minimum storage temperature -10 o C* (14 o F)Maximum storage temperature 60 o C (140 o F)

Initial flow rate

2.5L/min@0.25 Bar 1

Cartridge service rating 4000 litres (1056 US gallons) MWCO

200KDa – on dextranes Bacteria retention >99.999995 % (log 7.5)2Virus retention >99.999 % (log5)

Chemical reduction

A

ctivated carbon reduces chemical residues, inc; pesticides, endocrine disrupting

compounds, medical residues and heavy metals

LIFESAVER bottle US compliance

E

PA - US National Primary Drinking Water Regulations under the Safe Drinking Water Act 9 -52

LIFESAVER bottle UK compliance Water Supply (Water quality) Regulations 2000LIFESAVER bottle EU compliance European Drinking Water Directive Council Directive 98/8 /EC LIFESAVER bottle WHO compliance g uidelines for Drinking-water quality First

Addendum rd Edition Membrane approvals/compliances CE, EP A, NSF , WHO, WRAS, DVgW , KIWA, KTW , LSHTM Dry weight of bottle inc. cartridge 6 5 grams approx (approx 22 oz)Bottle storage capacity

750ml (1.6 US pints)

T E C H N I C A L I N F O R M A T I O N

18

T e

s t

e d &C e r t i f

i

e d

b y

1

Flow rates and capacity depend on the quality of the feed water 2

T ested by London School of Hygiene & T ropical Medicine using Escherichia coli NCTC 10418 in accordance with the Protocol for Microbiological Water Purifiers in accordance with US Environmental Protection Agency (EPA) guidelines.

3

T ested by London School of Hygiene & T ropical Medicine using

Poliovirus T ype 1 (Sabin vaccine strain) in accordance with the Protocol for Microbiological Water Purifiers in accordance with US Environmental Protection Agency (EPA) guidelines.

* After first use the product should be protected against freezing

UK international limited Warranty

Thanks again for purchasing LIFESAVER bottle. If you have any

questions relating to this or any other product in our range please

contact us via our website where we will be more than happy to help. LIFESAVER bottle comes with a 2 year international warranty from the

date of purchase against defects in materials and workmanship. Should

your LIFESAVER bottle prove defective within 2 years from the date of purchase you should return it to the retailer that you originally purchased

it from. LIFESAVER systems will, at its sole discretion, repair or replace

the damaged item(s).

you should ensure that you retain your proof of purchase showing the date on which you purchased your LIFESAVER bottle. Without it we are unable to offer warranty assistance. This International Limited Warranty does not affect your statutory legal rights.

Contact LIFESAVER systems

Customer Care

The Old Bakery

7 T uddenham Avenue

Ipswich

Suffolk

IP4 2HE

great Britain

I N

T

E

R N

A

T

I O N

A

L

L

I M

I

T

E D W

A

R

R

A N

T

y 19

DISCLAIMER:

The information and data contained in this document are based on our general experience

and are believed to be correct. They are given in good faith and are intended to provide a guideline for the selection and use of our products. Since the conditions under which our product may be used are beyond our control, this information does not imply any guarantee of final product performance and we cannot accept any liability with respect to the use of our products. The quality of our products is guaranteed under our conditions of sale. Existing industrial property rights must be observed.

LIFESAVER, LIFESAVER bottle, LIFESAVER cartridge 6000UF, LIFESAVER cartridge 4000UF, FOR A HOSTILE WORLD, FILL?PUMP?DRINK, Instructicons and FAILSAFE

are all trademarks and are used under licence with permission of their owners.

? 2007/2008 LIFESAVER systems. All Rights Reserved. International Patents Pending.

All details given on and in this manual are believed to be correct at the time of going to press. We reserve the right to make improvements and/or modifications to the equipment herein.

v1.

关于发酵罐的控制系统

关于发酵罐的控制系统 一参数控制 1温度控制 a 信号输入为4-20mA电流,对应输出为0-150℃温度 b 输出温度需通过校对调整,可编在程序内,也可以做个人机界面,使用人调整(a+bx) c 工作温度设定,通过人机界面由使用人输入 d 控制温度设定,分上限和下限,可采用工作温度加偏差温度(如0.5℃、1℃等)由使用人设定,也可以采用直接的温度值由使用人设定,也可以以0.5℃的偏差直接写入程序 e 控制方式:低于下限温度自动启动加热,高于上限温度自动启动冷却;加热和冷却过程需分别由使用人通过人机界面设定参数,参数为:加热时间(热水阀开启的时间,范围0-5分钟)和加热间隔时间(可设置为两次加热的间隔时间,也可以设置为热水阀关闭的时间,可以0-10分钟,由于加热过程中,热水进入发酵罐夹套后,发酵罐的温度上升要滞后一段时间,所以,关闭热水阀后要等一段时间,避免频繁启动而温度波动过大;同理,冷却过程也需要设置“冷却时间”和“冷却间隔时间” 2 酸碱度(pH)控制 a 信号输入为4-20mA电流,对应输出为0-14的pH值 b 输出pH需通过校对调整,需通过人机界面,使用人调整(a+bx) c pH值设定,通过人机界面由使用人输入 d 控制pH值设定,分上限和下限,可采用工作pH值加偏差pH值(如0.1、0.2等)由使用人设定,也可以采用直接的pH值由使用人设定, e 控制方式:低于下限pH值自动启动加碱,高于上限温度自动启动加酸;加碱和加酸过程需分别由使用人通过人机界面设定参数,参数为:加碱时间(加碱蠕动泵开启的时间,范围0-5分钟)和加碱间隔时间(可设置为两次加碱的间隔时间,也可以设置为加碱蠕动泵关闭的时间,可以0-10分钟,由于加碱过程中,氨水进入发酵罐后,发酵罐的pH值上升要滞后一段时间,所以,关闭加碱蠕动泵后要等一段时间,避免频繁启动而pH值波动过大;同理,加酸过程也需要设置“加酸时间”和“加酸间隔时间” 3 溶氧值(Do)控制 a 信号输入为4-20mA电流,对应输出为0-100的Do值 b 输出Do需通过校对调整,需通过人机界面,使用人调整(a+bx) c Do值设定,通过人机界面由使用人输入 d 控制Do值设定,分上限和下限,可以采用直接的Do值由使用人设定, e 搅拌电机的转速可设定为手动和自动,手动时由使用人通过人机界面直接输入,自动时则需要设定一个初始值和最低值,然后与溶氧(Do)相关联 f 控制方式:低于下限Do值自动启动搅拌电机加速,高于上限Do值自动启动搅拌电机减速;加速和减速过程需分别由使用人通过人机界面设定参数,参数

【CN209985950U】一种全自动发酵罐清洗系统【专利】

(19)中华人民共和国国家知识产权局 (12)实用新型专利 (10)授权公告号 (45)授权公告日 (21)申请号 201920437295.7 (22)申请日 2019.04.02 (73)专利权人 广州市科立盈喷淋设备有限公司 地址 510000 广东省广州市白云区嘉禾街 下村五社第二工业区168号B栋一至二 楼 (72)发明人 李高飞  (74)专利代理机构 广州市深研专利事务所 44229 代理人 张喜安 (51)Int.Cl. B08B 9/093(2006.01) (54)实用新型名称一种全自动发酵罐清洗系统(57)摘要一种全自动发酵罐清洗系统,涉及清洗设备的技术领域,其包括机架、握把、升降机构以及摆动机构,摆动机构包括摆动组件、阻挡组件、铰接机构、连接柱以及限位机构,所述限位机构包括连接框、滑槽、弹簧以及两组限位组件,所述连接框的内设有滑槽,滑槽内设有弹簧,弹簧的两端分别连接有两组限位组件,所述限位组件包括滑块以及限位辊;该全自动发酵罐清洗系统能够对喷嘴进行快速摆动,进而是喷嘴能够对发酵罐内的不同的位置进行清洗,不需要工作人员过多的体力劳动,清洗彻底且方便,通过限位机构的作用,能够对不同直径的连接有喷嘴的水管进行限位夹持,能够对水管进行有效限位固定,在喷嘴 喷水的过程中也不容易从限位机构上分离。权利要求书1页 说明书3页 附图4页CN 209985950 U 2020.01.24 C N 209985950 U

权 利 要 求 书1/1页CN 209985950 U 1.一种全自动发酵罐清洗系统,其特征在于:包括机架、握把、升降机构以及摆动机构,所述机架的一侧设有握把,机架的另一侧安装有升降机构,升降机构上安装有摆动机构,摆动机构包括摆动组件、阻挡组件、铰接机构、连接柱以及限位机构,所述摆动组件安装在升降机构上,摆动组件上连接有阻挡组件,阻挡组件的底部设有铰接机构,铰接机构的底部连接有连接柱,铰接机构的侧部连接有限位机构,所述限位机构包括连接框、滑槽、弹簧以及两组限位组件,所述连接框的内设有滑槽,滑槽内设有弹簧,弹簧的两端分别连接有两组限位组件,两组限位组件滑动连接于滑槽内,所述限位组件包括滑块以及限位辊,所述滑块的侧部连接于弹簧,滑块滑动连接于滑槽内,滑块中部铰接有限位辊,限位辊以滑槽的长度方向水平移动。 2.根据权利要求1所述的全自动发酵罐清洗系统,其特征在于:所述摆动组件包括支架、驱动机构、收集轴、导向轴A、导向轴B以及钢绳,所述支架安装在升降机构的输出端上,支架内设有驱动机构,驱动机构的输出端连接于收集轴,收集轴上缠绕有钢绳的一端,钢绳的另一端依次经过到导向轴A以及导向轴B,并最终与铰接机构连接,导向轴A安装在支架与阻挡组件的连接处,导向轴B安装在阻挡组件上。 3.根据权利要求2所述的全自动发酵罐清洗系统,其特征在于:所述阻挡组件包括圆板以及通孔,所述圆板的一侧固定安装在支架上,圆板与支架的连接处设有导向轴A,圆板的顶部设有导向轴B,所述圆板的远离机架的一侧设有数量为一个以上的通孔,一个以上的通孔均匀设置在圆板的边缘,圆板的底部固定连接有铰接机构。 4.根据权利要求3所述的全自动发酵罐清洗系统,其特征在于:所述铰接机构包括安装板、连接块、铰接部、连接板以及拉伸柱,所述安装板的顶部固定安装在圆板的底部,安装板的远离圆板的一侧设有连接块,连接块的底部设有铰接部,铰接部上铰接连接有连接板,连接板的一端设有与钢绳的末端连接的拉伸柱,连接板的另一端与连接框固定连接,连接板的底部固定连接于连接柱。 5.根据权利要求2所述的全自动发酵罐清洗系统,其特征在于:所述驱动机构为电机。 6.根据权利要求1所述的全自动发酵罐清洗系统,其特征在于:所述升降机构为气缸。 2

发酵罐的结构系统及使用

发酵罐的结构系统及使用.txt28 生活是一位睿智的长者,生活是一位博学的老师,它常常春风化雨,润物无声地为我们指点迷津,给我们人生的启迪。不要吝惜自己的爱,敞开自己的胸怀,多多给予,你会发现,你也已经沐浴在了爱河里。实验十五发酵罐的结构系统及使用方法一、实验目的: 1 .了解发酵罐(气升式、搅拌式)的几大系统组成,即空气系统、蒸汽系统、补料系统、进出料系统、温度系统、在线控制系统。2.掌握发酵罐空消的具体方法及步骤3.掌握发酵罐进料及实消的具体方法及步骤4.掌握发酵罐各系统的控制操作方法 二、实验原理: 1.蒸汽系统:三路进汽——空气管路、补料管路、罐体) 2.温度系统: (1)夹套升温:蒸汽通入夹套。 (2)夹套降温:冷水通入夹套,下进水,上出水。 (3)发酵过程自动控温系统:热电偶控温,马达循环,只能加热,发酵设定温度低于室温时,由夹套进冷水降温。 3.空气系统: 取气口T空压机:往复式油泵获得高脉冲的压缩空气 粗过滤器:由沙布包裹棉花压实成块状叠加制得,作用是去除部分细菌及大部分灰尘 (贮气罐):空压机压缩使气体温度升高,经贮气使气体保温杀菌;压缩空气中有油污、水滴,且压力不稳,有一定的脉冲作用,会冲翻后面的过滤介质,贮气后可使油滴重力沉降,减小脉冲。 冷却塔):有降温并稳定作用,同时经旋风分离器进行气液分离 (丝网分离器):通过附着作用,逐步累积沉降而分离5 微米以上的微粒其作用介质为铜丝网 (加温器):对压缩空气升温,除湿,使湿度达50%-60% 总过滤器:纱布包裹棉花加活性炭颗粒,逐层压紧而成。 分过滤器:平板式纤维,中间为玻璃纤维或丝棉,下面放水阀应适时打开放出油、水,再用压缩空气控干。

世界发酵罐

德国贝朗发酵罐 德国贝朗(Biostat B)为结构紧凑、罐体可高压灭菌、有数字检测和控制单元的台式发酵罐、基本设置有一般发酵过程所必需的所有探头和附件,其罐体工作体积分别为2立升、5立升或10立升,并有2立升和5立升气升式罐体可选择。 适用于科研和生产。它的主机部分和数字控制单元集于一箱体,以缩小占用的试验台操作面。标准化数字控制单元的控制参数包括温度、搅拌转速、PH、溶氧、泡沫和液面水平。Biostat B还内设可编程序蠕动泵四台、图线记录仪六通道)联接系统、串行(RS232)打印端面和串行主计算机联接系统。若用于细胞培养,Biostat B可提供低剪切桨式搅拌器,旋转滤器(Spinfiler)和无气泡通气系统,以及中空纤维培养系统(强化元件)。 Biostat B随时可联接上可供选择的各种气体混和系统。体积尺寸(长×高×宽mm):主机箱365×536×450,搅拌驱动装置(含支架)和罐体B2305×580×270/B5355×685×330/B10425×930×390。 美国NBS发酵罐 作为国际上著名的生物反应器生产厂家,NEW BRUNSWICK SCIENTIFIC CO., INC.是唯一能够向客户提供全面的微生物培养、植物细胞培养和动物细胞培养技术支持的公司,可向广大用户提供从实验室到中试和生产用的微生物、动物细胞、植物细胞培养的个系列发酵罐系统。公司本部拥有自己独立的细胞培养实验室和微生物发酵实验室,同时可向客户提供设备使用技术和培养技术的服务。 BioFlo 110型:是一种模块化的、组合式的高效微生物/细胞反应器,一台主控制器可以控制最多4套反应罐体同时工作,并可按实际需要提供微生物、动物细胞、植物细胞培养。罐体总体积范围:1.3L、3L、7.5L、14L、 BioFlo 310型:配置完善的标准型微生物/细胞反应器,可配备微生物反应罐体或细胞反应罐体,其控制系统相应的内置微生物培养和细胞培养二套不同的控制软件,合理的搅拌桨和罐体形状设计使得系统的传氧速率在350mMO2/L/Hr以上。对植物细胞培养,可配备相应的光照系统。罐体总体积范围:2.2L、5L、7.5L、14L BioFlo 410型:可在位灭菌微生物/细胞反应器,自带蒸汽发生装置,磁力驱动搅拌,不易染菌,升温/降温快速,适用于温度诱导型培养,大型彩色触摸控制屏,可显示各数据、及时值及趋势,并能模拟放大结果。罐体总体积范围:7L、14L、19.5L BioFlo 5000型:移动式中试微生物/细胞反应器,采用开放式框架结构,管道布局合理,维修简便,设计符合GMP标准。罐体总体积范围:40L、80L、120L BioFlo Pro型:工业用微生物/细胞反应器,是为满足工业生产要求而设计,符合GMP标准,结构简单合理,控制稳 定可靠,数据采集方便,PLC控制方式,扩展性强,其所有控制元件均采用工业通用配件,采购容易,更换维修方便,并可按照用户的使用要求定制。罐体总体积范围: 75L、150L、300L、500L、1000L、1500L 瑞士比欧发酵罐

发酵罐温度控制系统讲解

题目:发酵罐温度控制系统设计

课程设计(论文)任务及评语院(系):教研室:Array 注:成绩:平时40% 论文质量40% 答辩20% 以百分制计算

摘要 本题要设计的是温度控制系统,发酵是放热反应的过程。随着反应的进行,罐内的温度会逐渐升高。而温度对发酵过程具有多方面的影响。因此,对发酵过程中的温度进行检测和控制就显得十分重要。 本课题设计了发酵罐温度控制系统,选择的传感器为Cu100,由于信号很小,所以就需要通过差动放大电路进行放大并且经过了滤波电路滤波,然后将处理后的电压信号经过V/I转换,输出4~20mA的电流信号,最后进行仿真分析以及参数的计算,以达到通过对冷水阀开度的控制对发酵罐温度控制的目的。 本系统应用温度控制系统,有助于提高发酵效率,有助于提高工厂产值,并且可以使资源得到更充分的作用。 关键词:温度控制;PID控制器;V/I转换;比较机构

目录 第1章绪论 (1) 第2章课程设计的方案 (2) 2.1 概述 (2) 2.2 系统组成总体结构 (2) 2.3 传感器选择 (2) 第3章电路设计 (4) 3.1 传感器电路 (4) 3.2 比较机构电路 (7) 3.3 PID调节器并联实现电路 (7) 3.4 V/I转换电路 (8) 3.5 直流稳压电源电路 (9) 第4章仿真与分析 (10) 4.1 传感器电路仿真 (10) 4.2 PID控制器电路 (11) 4.3 V/I转换电路 (12) 第5章课程设计总结 (14) 参考文献 (15) 附录Ⅰ (16) 附录Ⅱ (18) 附录Ⅲ (20)

第1章绪论 在工业生产中,电流、电压、温度、压力、流量、流速和开关量都是常用的主要被控参数。其中,温度控制也越来越重要。在工业生产的很多领域中,人们都需要对各类加热炉、热处理炉、反应炉、发酵罐和锅炉中的温度进行检测和控制。 本次课设要求设计发酵罐的温度控制系统。发酵是放热反应的过程。随着反应的进行,罐内的温度会逐渐升高。而温度对发酵过程具有多方面的影响:它会影响各种酶反应的速率,改变菌体代谢产物的合成方向,影响微生物的代谢调控机制,除这些直接影响外;温度还对发酵液的理化性质产生影响,如发酵液的粘度;基质和氧在发酵液中的溶解度和传递速率。某些基质的分解和吸收速率等,进而影响发酵的动力学特性和产物的生物合成。 并且现代发酵工程不但应用于生产酒精类饮料、醋酸和面包,而且还可以生产胰岛素、干扰素、生长激素、抗生素和疫苗等多种医疗保健药物,天然杀虫剂、细菌肥料和微生物除草剂等农用生产资料,在化学工业上生产氨基酸、香料、生物高分子等。而发酵过程是酵母在一定的条件下,利用可发酵性物质而进行的正常生命活动。 发酵工程是应用生物(主要是微生物)为工业大规模生产服务的一门工程技术,也称微生物工程。发酵工程是包括微生物学、化学工程、基因工程、细胞工程、机械工程和计算机软硬件工程的一个多学科工程。 在发酵罐温度控制系统中应用最为广泛的调节器控制规律为比例、积分、微分控制,简称PID控制,又称PID调节。PID控制器是工业控制的主要技术之一。当被控对象的结构和参数不能完全掌握,或得不到精确的数学模型,控制理论的其他技术也难以采用,系统控制器的结构和参数必须依靠经验和现场调试来确定时,应用PID控制技术最为方便。采用PID算法进行温度控制,它具有控制精度高,能够克服容量滞后的特点,特别适用于负荷变化大、容量滞后较大、控制品质要求又很高的控制系统。 本次课设要求自行设计模拟式PID控制器,通过与前面传感器测定的发酵罐温度产生的电压信号进行比较,转换为输出时的4~20mA电流信号来对冷水阀门开度进行控制,采用冷水法对发酵罐进行降温,以达到对发酵罐温度进行控制的目的。参数要求测定范围是30℃~50℃,测量精度为±0.5℃,以此作为对温度传感器的选择依据。

2019最新范文-发酵罐的维护保养知识

发酵罐的维护保养知识 1、发酵罐精密过滤器,一般使用期限为半年。如果过滤阻力太大或失去过滤能力致影响正常生产,则需清洗或更换(建议直接更换,不作清洗,因清洗操作后不能可靠保证过滤器的性能)。 2、清洗发酵罐时,请用软毛刷进行刷洗,不要用硬器刮擦,以免损伤发酵罐表面。 3、发酵罐配套仪表应每年校验一次,以确保正常使用。 4、发酵罐的电器、仪表、传感器等电气设备严禁直接与水、汽接触,防止受潮。 5、发酵罐停止使用时,应及时清洗干净,排尽发酵罐及各管道中的余水;松开发酵罐罐盖及手孔螺丝,防止密封圈产生永久变形。 6、发酵罐的操作平台、恒温水箱等碳钢设备应定期(一年一次)刷油漆,防止锈蚀。 7、经常检查减速器油位,如润滑油不够,需及时增加。 8、定期更换减速器润滑油,以延长其使用寿命。 9、如果发酵罐暂时不用,则需对发酵罐进行空消,并排尽罐内及各管道内的余水。 二、发酵罐使用注意事项 1、必须确保发酵罐的所有单件设备能正常运行时使用本系统。 2、在消毒过滤器时,流经空气过滤器的蒸汽压力不得超过 0.17MPa,否则过滤器滤芯会被损坏,失去过滤能力。 3、在发酵过程中,应确保罐压不超过0.17MPa。

4、在实消过程中,夹套通蒸汽预热时,必须控制进汽压力在设备的工作压力范围内(不应超过0.2MPa),否则会引起发酵罐的损坏。 5、在空消及实消时,一定要排尽发酵罐夹套内的余水。否则可能会导致发酵罐内筒体压扁,造成设备损坏;在实消时,还会造成冷凝水过多导致培养液被稀释,从而无法达到工艺要求。 6、在空消、实消结束后冷却过程中,严禁发酵罐内产生负压,以免造成污染,甚至损坏设备。 7、在发酵过程中,发酵罐的罐压应维持在0.03~0.05MPa之间,以免引起污染。 8、在各操作过程中,必须保持空气管道中的压力大于发酵罐的罐压,否则会引起发酵罐中的液体倒流进入过滤器中,堵塞过滤器滤芯或使过滤器失效。 9、如果遇到自己解决不了的问题请直接与发酵罐的售后服务部门联系。请勿强行拆卸或维修发酵罐。

发酵罐温度控制系统的设计

洛阳理工学院 计算机控制技术与应用课程设计 题目:发酵培养基温度控制系统设计 学生姓名: 学号: 班级: 专业:

摘要 本题要设计的是发酵培养基温度控制系统,发酵是放热反应的过程。随着反应的进行,罐内的温度会逐渐升高。而温度对发酵过程具有多方面的影响。因此,对发酵过程中的温度进行检测和控制就显得十分重要。 本课题设计了发酵罐温度控制系统,选择的传感器为Cu100,由于信号很小,所以就需要通过差动放大电路进行放大并且经过了滤波电路滤波,然后将处理后的电压信号经过V/I转换,输出4~20mA的电流信号,最后进行仿真分析以及参数的计算,以达到通过对冷水阀开度的控制对发酵罐温度控制的目的。 本系统应用温度控制系统,有助于提高发酵效率,有助于提高工厂产值,并且可以使资源得到更充分的作用。 关键词:温度控制,PID控制器,V/I转换,比较机构

目录 前言........................................................................................ 错误!未定义书签。 1.1.1 发酵培养基简介 3 1.1.2工艺背景:................................................................ 错误!未定义书签。 1.2温度对发酵的影响...................................................... 错误!未定义书签。 1.2.1温度影响微生物细胞生长................................. 错误!未定义书签。 1.2.2温度影响产物的生成量..................................... 错误!未定义书签。 1.2.3温度影响生物合成的方向................................. 错误!未定义书签。 1.2.4温度影响发酵液的物理性质............................. 错误!未定义书签。 1.3、影响发酵温度变化的因素:..................................... 错误!未定义书签。 1.4发酵热的测定................................................................ 错误!未定义书签。 1.5最适温度的选择与发酵温度的控制............................ 错误!未定义书签。 1.5.1温度的选择....................................................................................... VII 2 培养基温度控制系统的设计.................................................. 错误!未定义书签。 2.1总体设计方案.............................................................................................. VII 2.1.1 系统总框图...................................................................................... VII 2.2硬件设计................................................................................................... V III 2.2.1温度采集电路.................................................................................. V III 2.2.2 PLC与计算机的通信......................................................................... I X 2.3软件部分......................................................................................................... X 3总结........................................................................................................................ X III 参考文献:............................................................................................................... X III

发酵罐的使用及其注意事项

一、准备 1、检查蒸汽管道、阀门、电机、电源、饮用水管是否有泄漏点或接通;如果有的管有泄漏点,及时更换乳胶管! 2、检查发酵罐轴封、夹层、搅拌、视镜阀是否正常;出现异常则及时添加甘油(密封用)。 3、用自来水清洗洁净本机内壁;一般上午开机后清洗3-5次,直至流出的水清亮为止。 4、用蒸汽空消发酵罐设施及相关管道系统; 5、拧开投料口盖镙栓,启动饮用水泵电源按钮,按工艺要求加入饮用水和投入生产用原、辅物料,拧紧投料口盖镙栓; 6、关循环水进水阀,开排水阀,将夹层储水排干净; 7、检查机器各部份紧固件是否松动和齐全。乳胶塞子要及时更换新的,避免染菌造成不必要的麻烦!! 补充:空消 在投料前,气路、料路、种子罐、发酵罐、碱罐、消泡罐必须用蒸汽进行灭菌,消除所有死角的杂菌,保证系统处于无菌状态。 1. 空气管路的空消 (1) 空气管路上有三级预过滤器,冷干机和除菌过滤器。预过滤器和冷干机不能用蒸汽灭菌,因此在空气管路通蒸汽前,必须将通向预过滤器的阀门关闭,使蒸汽通过减压阀、蒸汽过滤器然后进入除菌过滤器。 (2) 除菌过滤器的滤芯不能承受高温高压,因此,蒸汽减压阀必须调整在0.13Mpa,不得超过0.15MPa。 (3) 空消过程中,除菌过滤器下端的排气阀应微微开启,排除冷凝水。

(4) 空消时间应持续40分钟左右,当设备初次使用或长期不用后启动时,最好采用间歇空消,即第一次空消后,隔3~5小时再空消一次,以便消除芽孢。 (5) 经空消后的过滤器,应通气吹干,约20~30分钟,然后将气路阀门关闭。 2. 种子罐、发酵罐、碱罐及消泡罐空消 (1) 种子罐、发酵罐、碱罐及消泡罐是将蒸汽直接通入罐内进行空消。 (2) 空消时,应将罐上的接种口,排气阀,及料路阀门微微打开,使蒸汽通过这些阀门排出,同时保持罐压为0.13~0.15Mpa。 (3) 空消时间为30~40分钟,特殊情况下,可采用间歇空消。 (4) 种子罐、发酵罐、碱罐及消泡罐空消前,应将夹套内的水放掉。 (5) 空消结束后,应将罐内冷凝水排掉,并将排空阀门打开,防止冷却后罐内产生负压、损坏设备。 (6) 空消时,溶氧、PH电极取出,可以延长其使用寿命。 二、开机 置设备状态标志为使用状态;启动搅拌控制键按钮。 三、使用 1 、空气分过滤器灭菌; 2 、关空气进气阀,开排气阀,待压力降为零; 3、开蒸汽进汽阀,排汽阀开1/4圈,压力升至0.2Mpa时,进入实罐灭菌;

发酵罐操作操作规范

发酵罐操作流程 1 技术准备 发酵罐使用之前,应先检查电源是否正常,空压机、循环水系统是否能正常工作。同时要检查管道是否通畅及废水废气管道的完好情况。 2 空消 在投料前,气路、料路、发酵罐罐体必须用蒸汽进行灭菌,消除所有死角的杂菌,保证系统处于无菌状态。 2.1 空消步骤 打开蒸汽总开关----打开排冷凝水阀-------打开蒸汽过滤器开关------关闭预过滤器开关---打开空气精过滤器开关---打开进罐空气阀---打开空气排气阀---打开上分气包进发酵罐蒸汽阀---打开取料口进罐蒸汽阀---打开取样口排气----打开上分汽包进下分汽包阀---打开下分汽包总开关---打开下面进罐体蒸汽阀---打开接菌口和流量计出的排气阀。 2.2 空消注意事项 2.2.1 空气管路上有预过滤器和空气过滤器,预过滤器不能用蒸汽灭菌,因此在空气管路通蒸汽前,必须将预过滤器的阀门关闭。 2.2.2 空消时,应将罐上的接种口、排气阀及料路阀门微微打开,使蒸汽通过这些阀门排出,同时保持罐压为 0.13~0.15Mpa,空消时间为50分钟,夹层排水阀一直打开。 2.2.3 经常用手感受进蒸汽管道的畅通。 2.2.4 发酵罐空消前,应将夹套内的水放掉。空消结束后,应将罐内冷凝水排掉。 2.2.5空消结束后要通入无菌风吹干管路,并且管路和罐体要始终保持正压,以免杂菌的进入。 3 罐体实消 实消是当罐内加入培养基后,用蒸汽对培养基进行灭菌的过程。空消结束后,罐体压力降至0.03Mpa,打开罐体下面出料口排水阀排冷凝水,待排完后,关紧出料口阀门。打开进料口,加入培养基,拧紧。 3.1 实消步骤 开启机械搅拌装置---打开蒸汽总开关---打开拍冷凝水阀---打开上分气包进发酵罐蒸汽阀---打开夹层蒸汽阀 ---打开排气口排罐体冷空气---夹层温度达到95℃时关闭夹层蒸汽阀---打开罐体上面进蒸汽阀---打开上分汽包进下分汽包阀---打开下分汽包总开关---打开下面进罐体蒸汽阀---罐体压力达到0.15Mpa时开始计时,通过调节蒸汽阀保压30分钟。

发酵罐

发酵罐 德国赛多利斯公司 德国贝朗发酵罐 美国NBS公司 瑞士比欧生物工程公司 瑞士伊孚森生物技术(中国)有限公司 法国宝乐菲 意大利SOLARIS 索拉利斯 参数:在位灭菌 标准化数字控制单元的控制参数包括温度、搅拌转速、PH、溶氧、泡沫和液面水平规格:5,10,20,30L 德国贝朗发酵罐 德国贝朗(Biostat B)为结构紧凑、罐体可高压灭菌、有数字检测和控制单元的台式发酵罐、基本设置有一般发酵过程所必需的所有探头和附件,其罐体工作体积分别为2立升、5立升或10立升,并有2立升和5立升气升式罐体可选择。 适用于科研和生产。它的主机部分和数字控制单元集于一箱体,以缩小占用的试验台操作面。标准化数字控制单元的控制参数包括温度、搅拌转速、PH、溶氧、泡沫和液面水平。 Biostat B还内设可编程序蠕动泵四台、图线记录仪六通道)联接系统、串行(RS232)打印端面和串行主计算机联接系统。若用于细胞培养,Biostat B可提供低剪切桨式搅拌器,旋转滤器(Spinfiler)和无气泡通气系统,以及中空纤维培养系统(强化元件)。 Biostat B随时可联接上可供选择的各种气体混和系统。体积尺寸(长×高×宽mm):主机箱365×536×450,搅拌驱动装置(含支架)和罐体B2305×580×270/B5355×685× 330/B10425×930×390。 美国NBS发酵罐 作为国际上著名的生物反应器生产厂家,NEW BRUNSWICK SCIENTIFIC CO., INC.是唯一能够向客户提供全面的微生物培养、植物细胞培养和动物细胞培养技术支持的公司,可向广大用户提供从实验室到中试和生产用的微生物、动物细胞、植物细胞培养的个系列发酵罐系统。公司本部拥有自己独立的细胞培养实验室和微生物发酵实验室,同时可向客户提供 设备使用技术和培养技术的服务。 BioFlo 110型:是一种模块化的、组合式的高效微生物/细胞反应器,一台主控制器可以控制最多4套反应罐体同时工作,并可按实际需要提供微生物、动物细胞、植物细胞培养。 罐体总体积范围:1.3L、3L、7.5L、14L、 BioFlo 310型:配置完善的标准型微生物/细胞反应器,可配备微生物反应罐体或细胞反应罐体,其控制系统相应的内置微生物培养和细胞培养二套不同的控制软件,合理的搅拌桨和罐体形状设计使得系统的传氧速率在350mMO2/L/Hr以上。对植物细胞培养,可配备相应的光照系统。罐体总体积范围:2.2L、5L、7.5L、14L BioFlo 410型:可在位灭菌微生物/细胞反应器,自带蒸汽发生装置,磁力驱动搅拌,不易染菌,升温/降温快速,适用于温度诱导型培养,大型彩色触摸控制屏,可显示各数据、

大型发酵罐设计及实例

大型发酵罐设计及实例 上海医药工业设计院(200040) 石荣华 全国化工设备设计技术中心站(200040) 虞军 随着生化技术的提高和生化产品的需求量不断增加,对发酵罐的大型化、节能和高效提出了越来越高的要求。目前国际抗生素发酵罐的容积以80~200 米3 为主,而轻工的氨基酸、柠檬酸的发酵罐较普遍使用150~300 米3 ,国际上最大标准式发酵罐为美国ADM 公司赖氨酸发酵罐,其容积为10 万加仑,折合公称容积为380 米3 。众所周知发酵是一个无菌的通气(或厌氧) 的复杂生化过程,需要无菌的空气和培养基的纯种浸没培养,因而发酵罐的设计,不仅仅是单体设备的设计,而且涉及培养基灭菌、无菌空气的制备、发酵过程的控制和工艺管道配制的系统工程。 1 国内发酵罐现况 改革开放后,国内发酵罐的装备得到了显著改善,具体表现在: 容积:抗生素发酵扩大至100~150m3 。 赖氨酸发酵已达200m3 。 材质:逐步由碳钢改为不锈钢。 传热:由单一的罐内多组立式蛇管改为罐壁半圆形外盘管为主,辅之罐内冷却管。 减速机:由皮带减速改为齿轮减速机。 搅拌机:由单一径向叶轮改为轴向和径向组合型叶轮。 但由于发酵罐的系统设计没有受到人们普遍重视,有许多抗生素生产人员往往仅重视发酵工艺和菌种,或 限于资金和发酵厂房现状,对发酵罐的大型化和优化缺乏足够重视。就发酵罐而言,目前头国内基本上在原有50m3 基础上进行改革, 罐径为3.00 毫米,罐筒体略有变化,形成57m3 、60m3 等罐体,电机相应作些变化有75 、95 和1.5kW 不等,传热为立式蛇管和搅拌叶轮基本不变为六叶蜗轮,减速采用皮带轮。因而同国际上存在不少的差距,有必要通过对发酵罐系统设计的认识提高,将我国抗生素发酵装备水平向前推进。 2 发酵罐的设计 2.1 发酵罐的型式 发酵过程可以通过固体培养和深层浸没培养来完成,从生产工艺来说可分为间隙分批、半连续和连续发酵等,但是工业化大规模的发酵过程,则以通气纯种培养为主。 通过纯种培养的发酵罐有自吸式发酵罐、标准式发酵罐、气升式发酵罐、喷射式叶轮发酵罐、外循环发酵罐和多孔板塔式发酵罐等。自吸式发酵罐系通过发酵罐内叶轮的高速转动,形成真空将空气吸入罐内,由于叶轮转动产生的真空,其吸入压头和空气流量有一定限制,因而仅适用对通气量要求不高的发酵品种;塔式发酵罐是将发酵液置于多层多孔塔板的细长罐体内,在罐底部通入无菌空气,通过气体分散进行氧的传递,但其供氧量也受到一定限度; 气升式发酵罐、喷射式叶轮发酵罐、外循环发酵罐均是通过无菌空气在罐内中央管或通过旋转的喷射管和罐外喷射泵将发酵液进行一定规律的运动,从而达到气液传质,目前气升式发酵罐在培养基较稀薄,供氧量要求不过分高的条件下(如(V1C 发酵) 得到了较为广泛使用,其它喷射式叶轮发酵罐、外循环发酵罐也有一定的用途;但在发酵工业中,仍数兼具通气又带搅拌的标准式发酵罐用途最为普遍,标准式发酵罐被广泛使用抗生素、氨基酸、柠檬酸等各个领域。 2.2 标准式发酵罐 随着发酵产品需求量增加,发酵过程控制和检测水平提高,发酵机理的了解和最优化的机理认识水平提高,以及空气无菌处理技术水平的提高,发酵罐的容积增大已成为抗生素工业的趋势。 2.2.1 罐的几何尺寸 主要是关心发酵罐的H/ D ,一般随着罐体高度和液层增高、氧气的利用率将随之增加,容积传氧系数KLa 随之提高,但其增长关系不是线性关系,随着罐体增高, KLa 的数值增长速率随之减慢,而随着罐体容积增大,液柱增高,进罐的空气压力随之提高,伴随空压机的出口压力提高和能耗的增加,而且压力过大后,特别是 在罐底气泡受压后体积缩小,气液界面的面积可能受到影响,过高的液柱高度,虽增加了溶氧的分压,但同

进口发酵罐比较

发酵罐中德国贝朗、瑞士比欧、美国NBS和荷兰Applikon的比较 发布: 2008-7-31 18:12 | 作者: lwdfjw | 来源: 发酵人门户博客 我是江苏省农科院,实验室打算买两台进口发酵罐,现在在德国贝朗、瑞士比欧、美国NBS 和荷兰Applikon这四个品牌作选择。想问问前辈这四个品牌的优缺点,请各位给个客观的 比较。 lwdfjw 2008-7-31 19:02:01 意★轩辕(63672175) 18:50:05 贝朗参数最稳定,使用最方便,是标准发酵的首选,价位最高。 意★轩辕(63672175) 18:51:34 比欧配套装置最齐全,可检测参数最完整,适合动力学研究 意★轩辕(63672175) 18:52:04 NBS比较实惠,但看起来不那么好看,性价比比较好,性能一般 意★轩辕(63672175) 18:53:17 建议买比欧,当然所有配件最好配齐,价格偏高,但性能还不错!贝朗的故障率最低,用了这么就没出过任何故障 意★轩辕(63672175) 18:53:25 鉴定完毕 品牌德国贝朗 美国NBS 瑞士比欧 型号BIOSTAT? Bplus 5L细胞培养反应 器 NBS Bioflo 310 型 R’A LF-PLUS 罐体材质:培养基接触面,不锈钢1.4435 (316L);硼硅玻璃;圆底带有夹套 的玻璃罐体,总体积 6,6 L,工作体积 0,4 - 5,0 L;需要高压灭菌锅尺寸:高 度700mm,直径300mm 罐体:总容积:7.5L; 工作容积:Max. 5L 6.7L总容积,约4.5L工作容 积,圆柱罐体,温控夹套, 用于温度控制。 罐盖带垂直把手的不锈钢顶盖,传动轴与 顶盖连接紧密;电机与传动轴可以方 便实 现多点偶合传动。 不锈钢罐盖,包括各 种夹子和连接管道 316L不锈钢材质,配最少9 *12mm无菌耐压孔,1个上 搅拌孔,2-路连接孔用于培 养基/酸的补加,另2-路孔用 于碱/消泡剂补加,高度可调 节的收液管(液位浸没管) 带2-路连接件用于取样接

发酵罐温度控制系统设计

内蒙古科技大学 过程控制工程课程设计说明书 题目:发酵罐温度控制系统的设计 学生姓名: 学号: 专业:测控技术与仪器 班级:2009-3 指导教师:

目录 前言........................................................................................ 错误!未定义书签。1工艺过程概述........................................................................... 错误!未定义书签。 1.1工艺背景:.................................................................. 错误!未定义书签。 1.2温度对发酵的影响...................................................... 错误!未定义书签。 1.2.1温度影响微生物细胞生长................................. 错误!未定义书签。 1.2.2温度影响产物的生成量..................................... 错误!未定义书签。 1.2.3温度影响生物合成的方向................................. 错误!未定义书签。 1.2.4温度影响发酵液的物理性质............................. 错误!未定义书签。 1.3、影响发酵温度变化的因素:..................................... 错误!未定义书签。 1.4发酵热的测定................................................................ 错误!未定义书签。 1.5最适温度的选择与发酵温度的控制............................ 错误!未定义书签。 1.5.1温度的选择 (4) 2 发酵罐温度控制系统的设计.................................................. 错误!未定义书签。 2.1总体设计方案 (4) 2.1.1 系统总框图 (5) 2.2硬件设计 (6) 2.2.1温度采集电路 (6) 2.2.2 PLC与计算机的通信 (6) 2.3软件部分 (7) 3总结 (11) 参考文献: (12)

发酵罐使用说明书

发酵罐说明书 一、概述 该系统发酵罐是通用型机械搅拌罐,采用无级变速调节搅拌转速。广泛用于有机酸、酵母、酶制剂、维生素等生物制品的生产。 二、系统组成 该系统发酵罐可由种子罐、发酵罐、补料罐、碱罐、泡敌罐、空气除菌过滤系统、蒸汽灭菌系统、温度控制系统、PH测量系统、溶解氧测量系统、微机控制系统等部分组成。各系统的流程及工作参数如下: 1. 空气除菌过滤系统 无油空气压缩机(0.5~0.6 Mpa) 贮气罐 有油空气压缩机(0.5~0.6 Mpa)→油水分离器 一级预过滤→冷干机→二级预过滤→三级预过滤→减压阀(0.25 ~0.3Mpa)→ 除菌过滤器1→种子罐 总除菌过滤器 除菌过滤器2→发酵罐 2. 蒸汽灭菌系统 种子罐、发酵罐灭菌(0.3MPa) 蒸汽锅炉 减压阀(≤0.13Mpa)→蒸汽过滤器 除菌过滤器1 除菌过滤器2 3. 温度控制系统 种子罐夹套 控温水箱→循环水泵→ 发酵罐夹套 4. PH测量系统 发酵罐PH电极→仪表显示→微机采集→数据查询、曲线分析 5. 溶解氧测量系统 发酵罐溶解氧电极→仪表显示→微机采集→数据查询、曲线分析 6. 消泡系统 发酵罐泡沫传感器→反馈给微机→报警 三、主要技术参数 1. 种子罐:灭菌压力≤0.15Mpa:工作压力:0.05~0.07Mpa 灭菌温度:121℃~125℃

2. 发酵罐:灭菌压力≤0.15 Mpa:工作压力:0.05~0.07Mpa 灭菌温度:121℃~125℃ 3. 碱罐:灭菌压力≤0.15 Mpa:工作压力:0.05~0.07Mpa 灭菌温度:121℃~125℃ 4. 消泡罐:灭菌压力≤0.15 Mpa:工作压力:0.05~0.07Mpa 灭菌温度:121℃~125℃ 5. 进罐空气压力:种子罐、发酵罐、0.25MPa。 6. 空压机:容积排气量> m3/min (无油) 排气压力 0.6Mpa 7. 控温水箱电功率: Kw 8. 水循环泵:功率 Kw ;流量 m3/h 9. 转速:无级调速~ rpm 10. PH值:仪表显示并记录 11. 溶解氧值:仪表显示并记录 12. 罐温:仪表显示并记录 四、使用前的技术准备 1. 上岗前的技术培训:SFM—2000L等发酵罐是机电一体化的设备,因此;操作人员上岗前必须进行技术培训,使他们熟悉整个系统的工作原理、管路、阀门的操作程序,并对空压机,蒸汽锅炉、变频电机等设备,能正确操作使用。未经培训的人员,不得单独上岗操作。 2. 设备使用之前,应先检查电源是否正常,空压机、微机控制系统、循环水系统是否能正常工作。 3. 检查系统上的阀门、接头及紧固螺钉是否拧紧。 4. 开动空压机,用0.15Mpa压力,检查种子罐、发酵罐、过滤器、管路、阀门的密封性能是否良好。 5. 对温度仪、调速电机,电容涡街流量计应根据使用说明书进行检查、校正。 6. 上岗人员对上述各项必须能熟练操作。 五、空消 在投料前,气路、料路、种子罐、发酵罐、碱罐、消泡罐必须用蒸汽进行灭菌,消除所有死角的杂菌,保证系统处于无菌状态。 1. 空气管路的空消 (1) 空气管路上有三级预过滤器,冷干机和除菌过滤器。预过滤器和冷干机不能用蒸汽灭菌,因此在空气管路通蒸汽前,必须将通向预过滤器的阀门关闭,使蒸汽通过减压阀、蒸汽过滤器然后进入除菌过滤器。 (2) 除菌过滤器的滤芯不能承受高温高压,因此,蒸汽减压阀必须调整在0.13Mpa,不得超过0.15MPa。

最新发酵罐的结构系统及使用

发酵罐的结构系统及使用.txt28生活是一位睿智的长者,生活是一位博学的老师,它常常春风化雨,润物无声地为我们指点迷津,给我们人生的启迪。不要吝惜自己的爱,敞开自己的胸怀,多多给予,你会发现,你也已经沐浴在了爱河里。实验十五发酵罐的结构系统及使用方法 一、实验目的: 1.了解发酵罐(气升式、搅拌式)的几大系统组成,即空气系统、 蒸汽系统、补料系统、进出料系统、温度系统、在线控制系统。 2.掌握发酵罐空消的具体方法及步骤 3.掌握发酵罐进料及实消的具体方法及步骤 4.掌握发酵罐各系统的控制操作方法 二、实验原理: 1.蒸汽系统: 三路进汽——空气管路、补料管路、罐体) 2.温度系统: (1) 夹套升温:蒸汽通入夹套。 (2) 夹套降温:冷水通入夹套,下进水,上出水。 (3) 发酵过程自动控温系统:热电偶控温,马达循环,只能加热,发酵设定温度低于室温时,由夹套进冷水降温。 3.空气系统: 取气口→空压机:往复式油泵获得高脉冲的压缩空气 粗过滤器:由沙布包裹棉花压实成块状叠加制得,作用是去除部分细菌及大部分灰尘 (贮气罐):空压机压缩使气体温度升高,经贮气使气体保温杀菌;压缩空气中有油污、水滴,且压力不稳,有一定的脉冲作用,会冲翻后面的过滤介质,贮气后可使油滴重力沉降,减小脉冲。 (冷却塔):有降温并稳定作用,同时经旋风分离器进行气液分离 (丝网分离器):通过附着作用,逐步累积沉降而分离5微米以上的微粒 其作用介质为铜丝网

(加温器):对压缩空气升温,除湿,使湿度达50%-60% 总过滤器:纱布包裹棉花加活性炭颗粒,逐层压紧而成。 分过滤器:平板式纤维,中间为玻璃纤维或丝棉,下面放水阀应适时打开放出油、水,再用压缩空气控干。 种子罐或发酵罐 4.补料系统:补培养基、消泡剂、酸碱等。 5.在线控制系统:热电偶(温度探关)、溶氧探头、pH探头(后二者实消时才安装,为不可再生探头,有限定使用次数,pH探头使用前要先校准)、控制柜、数据采集系统。 6、进出料系统:进料口(接种口)、出料口(取样口)。 7.蒸汽过滤器:在蒸汽进入空气系统时应用,以免蒸汽中携带的杂质颗粒堵塞分过滤器微孔。 三、方法与步骤: (一)原则: 1.通蒸汽前先关闭所有阀门。 2.粗过滤器不空消也不实消,要定期处理,所以必须关闭通向粗过滤器的阀门。 3.活蒸汽,灭过头,即尾汽不能关死,要保证有活蒸汽放出,但不能太大,以免分压。4.罐体排汽口排汽,并保持罐内正压。 5.空气过滤系统只空消,不实消,以免罐中物料冲入过滤器内。但空消一结束,即要通入无菌空气吹干管路并保压,避免染菌。 6.进蒸汽时顺着蒸汽管路开阀门,结束时逆着进路关阀门,先开尾阀后开主阀,结束时先关主阀后关尾阀。 8.蒸汽一停,即由无菌空气充入保持罐内正压。 (二)空消: 先开启蒸汽发生器,自有蒸汽产生并排掉管路中冷凝水后,按以下步骤进行: 1.先关闭所有阀门,检查处是否关紧密封,打开罐上方排气口。 2.蒸汽先进空气系统,蒸汽→蒸汽过滤器→分过滤器,无论蒸汽走到哪一路得先放尾阀,放出冷凝水,排掉冷空气,待有蒸汽冲出后调小,打开主阀。 3.再进罐体:由主路进罐,然后通入取料管路,再入补料系统(两边)。 4.罐压升至0.12Mpa(此时控制系统中温度读数约为120℃左右)时开始计时,保温保压,30分钟。 保压方式:(1)调节主汽路进汽阀门控制进汽量;(2)调节排气口排气量大小或尾阀放汽量。

相关主题
相关文档
最新文档