液液微分散及其用于标准颗粒制备的研究进展
化
工进展CHEMICAL INDUSTRY AND ENGINEERING PROGRESS 2019年第38卷第1期液液微分散及其用于标准颗粒制备的研究进展李严凯，王凯，骆广生（清华大学化学工程联合国家重点实验室，北京100084）摘要：液液分散与液滴生成是化工生产最典型的多尺度动态过程之一，针对该类过程的精准控制是化工研究的难点与重点。近年来，伴随机械微加工与流体微量输运技术的快速兴起，基于微米尺度作用的微化工技术在液液分散与液滴生成的调控中展现出了显著优势，成为化工研究的前沿方向。本文针对近年来在微分散基本规律、微分散动态界面现象与微分散标准颗粒材料等领域的研究进展进行综述：围绕微分散基本规律，介绍了微尺度液滴破碎的主导作用力、液液微分散流型及微分散数值模拟方法；围绕微分散动态界面现象，分析了动态界面张力的变化规律及其影响因素；围绕微分散标准颗粒制备，简述了微分散颗粒制备的主流技术及其适用范围。同时，针对相关领域的发展方向进行了展望。关键词：微液滴；微分散；微流体学；传递过程；界面张力；标准颗粒中图分类号：TQ02文献标志码：A 文章编号：1000-6613（2019）01-0030-15Advances in liquid-liquid micro-dispersion and its applications in standard particle preparation LI Yankai ，WANG Kai ，LUO Guangsheng (State Key Laboratory of Chemical Engineering,Tsinghua University,Beijing 100084,China)Abstract:Liquid-liquid dispersion process is one of the most typical chemical engineering processes,and the precise control of such processes is the key point for chemical engineering research.Micro-structured chemical systems perform multi-scale manipulation of liquid-liquid multi-phase flows,and have been regarded as one of the most promising techniques for liquid-liquid dispersion and droplet generation.In this paper,recent progresses in droplet generation mechanism,dynamic interfacial tensions (IFTs)and standard particle preparation were introduced.Dominant forces of droplet rupture,flow patterns of liquid-liquid micro-dispersion and micro-dispersion computational fluid dynamics (CFD)methods were firstly introduced.Then,the mechanism of dynamic interfacial tensions (IFTs)were analyzed.Micro-dispersion techniques for particle preparation were finally stated.This review also presents outlook to the future research areas of micro-dispersion and particle preparation.Keywords:micro-droplet;micro-dispersion;microfluidics;transport process;interfacial tension;standard particle 液液分散及液滴生成是化工生产最典型的多尺度动态过程之一。化工反应过程中，液液分散与液滴生成的“特征尺度”通常在μm ～mm 级；同时，nm ～m 级的传质、传热、动量传递及化学反应过 特约评述DOI ：10.16085/j.issn.1000-6613.2018-1169收稿日期：2018-06-03；修改稿日期：2018-09-24。基金项目：国家自然科学基金（U1463208,91334201）。第一作者：李严凯（1992—），男，博士研究生。E-mail ：li-yk09@https://www.360docs.net/doc/d27983439.html, 。通信作者：骆广生，教授，博士生导师。E-mail ：gsluo@https://www.360docs.net/doc/d27983439.html, 。引用本文：李严凯,王凯,骆广生.液液微分散及其用于标准颗粒制备的研究进展[J].化工进展,2019,38(1):30-44.Citation ：LI Yankai,WANG Kai,LUO Guangsheng.Advances in liquid-liquid micro-dispersion and its applications in standard particle preparation [J].Chemical Industry and Engineering Progress,2019,38(1):30-44.··30万方数据