国外大学申请书的写法

国外大学申请书的写法
国外大学申请书的写法

Tips for Writing Letters of

Motivation

Language Department

Prof. Dr. Stephanie Swartz-Janat Makan

Letter of motivation

A letter of motivation (also called a "statement of purpose" or "personal essay") is a brief essay in which you explain what you hope to achieve during your studies or the scholarship program for which you are applying, as well as what it is that qualifies you as a top candidate for the scholarship.

The letter of motivation is an extremely important part of the application documents because it provides the selection committee with a description of your personality, as well as in what way you plan to contribute to and benefit from the scholarship program for which you are applying. Useful advice

?Make sure you know the exact format of the letter of motivation required by the competition before you start writing (required number of words/pages, spaces, etc.) ?Make sure your text is clear and readable

?Answer the questions: Why that country, why that university or company, what do you expect to gain by going abroad (mention concrete goals and benefits expected). Learning the language is not reason enough!

Here are some tips to keep in mind when writing a letter of motivation.

? A "letter of motivation" is your opportunity to "sell" yourself, i.e. convince the institution or company that they need to have you. Do not be modest: when applying, explain clearly why you think you are suited for the position or why the institution should support you.

?The goal of a letter of motivation is to provide a picture of your background and goals that will persuade the admission committee to accept you.

?Recruiters expect you to show that what you have matches what they want. Remember, this is a question of interpretation, and the secret of writing a good letter of motivation lies in using your qualifications and experience to show that you are the best person to support.

?Beyond the particular skills required by each program, a letter of motivation should show you to be a clear-headed person, capable of thinking clearly, and a motivated, active learner. Write in a clear and logical manner: remember, the way you write and present yourself says a lot about you.

?Before writing the first draft, take some time to think about yourself, your goals and your skills. Think about your background, what and where you have studied, and how all that

makes you suitable for the program/position. Put this in to the first part of the letter of motivation.

?Continue in the second section with your professional goals, explaining the connection between them and your studies. Present your long-term plans, and say how the program you are applying for will help you achieve those goals. Make clear why your background makes you suitable for the program, and how the program will help you achieve your long-term goals. In this section also explain why precisely that university etc. is your choice – the courses, faculty, research interests are possible reasons. In conclusion, state how you can contribute to the program.

?You need to take time. Expect to revise your letter up to 10 times (no exaggeration!) before you come up with a good letter. One strategy is, let it rest after you have written a new draft for a few days, and read it again, in order to get a more objective view. And have it checked by as many other people as possible! To do this, of course, means you must start the process early.

?And don't just copy what you have said in the other documents that you submit, but try to add to them. Answer the essay/statement question, if you have one - it usually will be something like "Why are you the right person for this program?".

Some important terminology:

I would like to apply …..

I am seriously considering specializing in …….

I am keenly interested in acquiring more theoretical/practical knowledge in ……

I would hope to be given the opportunity to …….

I would hope to be able to take part in …….

I am familiar with …….

It is my hope to learn more about ……. and experience other methods of …….

….. is my first choice as a foreign country because ……

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Coding-independent regulation of colon cancer cell proliferation PROJECT DESCRIPTION Colorectal Cancer (CRC), a malignant disease derived from colon epithelial cells, is one of the major threats to public health. Australia has one of the highest rates of CRC in the world. It is the third most common type of newly diagnosed cancer in the country. Moreover, it is the second most common cancer killer, claiming lives of around 3982 Australians each year. However, there is currently no curative treatment for metastatic colorectal cancers. Investigation of genes and signaling pathways that are dysregulated in CRC is a high priority for identification of novel therapeutic targets. Only 1.5% of the mammalian genome encodes proteins, and most of the genome is transcribed to tens of thousands of long (>200 nt) non-coding RNAs (lncRNAs). However, the functional consequence of the expression of lncRNAs has been largely uncharacterized. To date, a very small number of lncRNAs have been investigated, and their functional roles, revealed, in colon cancer. Preliminary studies from Professor Xu Dong Zh ang’s laboratory have shown that the expression of a lncRNA called REG1CP is elevated in five CRC tissues in comparison with adjacent non-cancerous colon epithelial tissues. The increase in REG1CP is further confirmed in a panel of CRC cell lines compared with a normal human colon cell line FHC. Of note, inhibition of REG1CP by siRNA reduced, whereas overexpression of REG1CP enhanced, CRC cell proliferation. To turn this information into our advantage in understanding CRC biology and in the treatment of the disease, we propose in this application to clarify the consequence of REG1CP upregulation and the mechanism involved in CRC cells, and to examine whether REG1CP-mediated signal is a potential therapeutic target in CRC. Our specific aims are to test whether targeting REG1CP inhibits proliferation of CRC cells and retards CRC xenograft growth in animal models, and to define the mechanism that drives the increase in REG1CP expression in CRC cells and the mechanism by which REG1CP regulates colon cancer growth. University of Newcastle has a strong cancer research program aiming to translate scientific advances into better clinical care. This project fits perfectly to the objectives of Cancer Program in that it will potentially lead to the development of new treatment approaches for CRC. Professor Xu Dong Zhang’s laboratory is highly experienced in similar studies, and it is well equipped with techniques and other materials and support needed for carrying out this project. Background: lncRNA: It has been recently shown that over 70% of the genomes of human and higher eukaryotes are transcribed, but only 1.5% of the human genome codes for proteins. lncRNAs are a large and diverse class of transcribed RNA molecules of more than 200 nucleotides that do not encode proteins, which may exert their functions either by binding to DNA or RNA in a sequence specific manner or by binding to proteins. lncRNA in cancer: Increasing evidence shows that lncRNAs play an important role in cancer biology. Dysregulated expression of lncRNAs in cancer frequently marks disease progression and often serves as an independent predictor for poor prognosis of cancer patients. (1, 2) REG1CP:REG1CP is an RNA that lacks an open reading frame. It is located to the locus enriched with regenerating (REG) gene family members, whose expression levels are closely associated with the survival rate of CRC patients (3). Interestingly, we have found REG1CP expression levels are positively related with the levels of REG gene family members including REG1A, REG1B and REG3A, suggesting that REG1CP may plays an important role in CRC patient survival as well. Supporting data: lncRNA microarray data showed that REG1CP was the most significantly upregulated lncRNA in five CRC tissues compared with adjacent non-cancerous colon epithelial tissues. While overexpression of REG1CP promotes, inhibition of REG1CP reduces, CRC cell proliferation. Moreover, REG1CP is also commonly upregulated in cultured CRC cell lines irrespective of their origins and genetic backgrounds in comparison with the cultured normal colon epithelial cell line FHC. Of note, REG1CP expression is positively associated with REG family members, which have been reported as predictors of poor CRC patient survival.

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